Xin Gu, MD

Dr. Gu finished his pathology residency training at LSU Health Sciences Center in June 2001, followed by a one year fellowship in renal pathology at LSUHSC. Prior to the pathology residency, Dr. Gu was involved in basic research at the University of Alabama at Birmingham (UAB), where his research work focused on cellular second messenger pathways and disease development. At LSUHSC, Dr. Gu focus is on renal and surgical pathology.

Training

1983 -
M.D. Capital University of Medical Sciences, Beijing, China

Previous positions within medical schools include:

1983 - 1987
Neurology Resident, Capital University of Medical Sciences, Beijing, China
1987 - 1989
Neurologist, Beiging Neurological Institute, Capital University of Medical Sciences, Beijing, China
1989 - 1996
Research Fellow, University of Alabama at Birmingham
1997 - 2001
Resident, Anatomical and Clinical Pathology, LSUHSC-Shreveport, LA
2001 - 2002
Fellow, Department of Pathology, LSUHSC-Shreveport, LA
2001 - 2006
Assistant Professor, Department of Pathology, LSUHSC-Shreveport, LA
2006 - Present
Associate Professor, Department of Pathology, LSUHSC-Shreveport, LA

Board Certifications

2001 -
Anatomic and Clinical Pathology

Research Interest

Renal pathology

Selected Publications

Book Chapters:

Gu X. Sarcoidosis. In: Diagnostic Pathology Kidney Diseases, Section 4, Tubulointerstitial Diseases: 4-102. Amirsys Inc, 2011.

Gu X. Loin Pain Hematuria Syndrome. In: Diagnostic Pathology Kidney Diseases, Section 7, Diseases of the Collecting System: 7-24. Amirsys Inc, 2011.

Herrera GA, Gu X. Medical Disease of the Kidney. In: Principles and Practice of Surgical Pathology and Cytopathology, 4th edition. Edited by Steven F. Silverberg. Elsevier Science. 2005.

Publications / Presentations / Abstracts / Posters:

Gu X, Jiang Ru, Fowler M. Acantholytic squamous cell carcinoma in upper aerodigestive tract: Histopathology, immunohistochemical profile and epithelial mesenchymal transition phenotype change. Head and Neck Pathology, E-publication ahead of print, available online: July 31, 2012.

Gupta V, Bhinge K, Xiong K, Gu X, Shi R, Ambudkar S, Jazwinski SM, Liu YY. Ceramide glycosylation by glucosylceramide synthase selectively maintains the properties of breast cancer stem cells. J Biol Chem, E-publication ahead of print, available online: Aug. 30, 2012.

Gu X, Liu XY, Fagan A, Gonzalez-Toldo ME, Zhao L-R. Ultrastructural changes in cerebral capillary pericytes in aged Notch3 mutant transgenic mice. Ultrastruct Pathol, 36:48-55, 2012.

Jiang R, Gu X, Moore-Medlin TN, Nahtan CA, Hutt-Fletcher L. Oral dysplasia and squamous cell carcinoma: correlation between increased expression of CD21, Epstein-Barr virus and CK19. Oral Oncology, 48:836-841, 2012.

Piazza A, Gu X, Kim RH. Sebaceous carcinoma of the right arm. J La State Med Soc. 164: 81-82, 2012.

Sequeira A, Buffington M, Gu X, Abreo K. Testicular angina during hemodialysis: An unusual complication of ultrafiltration. Hemodialysis Int, E-publication ahead of print, available online: Aug. 7, 2012.

Gu X, Eskandari F, Fowler MR. Sphenoid sinus basaloid squamous cell carcinoma presenting as a sellar mass: Report a case with review of the literature. Head and Neck Pathol. 5:81-85, 2011.

Liu YY, Patwardhan GA, Bhinge K, Gupta V, Gu X, Jazwinski SM. Suppression of glucosylceramide synthase restores p53-dependent apoptosis in mutant p53 cancer cells. Cancer Res. 39:425-431, 2011.

Bao JR, Anga A, Gu X, Zhang S, Coteligam J. An infant with recurrent maculopapular rashes, anemia, lymphadenopathy, and hepatosplenomegaly. J La State Med Soc. 163:140-143, 2011.

Liu YY, Patwardhan GA, Xie P, Gu X, Giuliano AE, Cabot MC. Glucosylceramide synthase, a factor in modulating drug resistance, is overexpressed in metastatic breast carcinoma. Int J Oncol. 71:2276-2285, 2011

Robbins D, Gu X, Runhua Shi, Liu JF, Wang F, Ponville J, McCord JM, Zhao Y. The chemopreventive effects of protandim: Modulation of p53 mitochondrial translocation and apoptosis during skin carcinogenesis. PloS One. 5 (7):e1902, 2010.

Patwardhan1 G, Gupta V, Huang J. Gu X, Liu YY. Direct assessment of P-glycoprotein efflux to determine tumor response to chemotherapy. Biochem Pharmacol. 80:72-79, 2010.

Gu X, Herrera GA. Expression of eNOS in kidneys from hypertensive patients. Int J of Nephrol Renovasc Dis. 3;11-19, 2010.

Zhao S, Gu X, Groome LJ, Wang Y. Decreased nephrin and GlEPP-1, but increased VEGF, Flt-1 and nitrotyrosine, expressions in kidney tissue from women with preeclampsia. Reprod Sci. 16:970-979, 2009.

Liu J, Gu X, Robbins D, Shi R, McCord JM, Zhao Y. Protandim, a fundamentally new antioxidant approach in chemoprevention using mouse tow-stage skin. PloS ONE. 4: e5284, 2009.

Jiang R, Gu X, Nahtan CA Hutt-Fletcher L. Laser-capture microdissection of epithelial cells in the oropharynx indicates restriction of expression of Epstein-Barr virus receptor/CD21 mRNA to tonsil epithelium. J Oral Pathol Med. 37:626-633, 2008.

Liu J, St. Clair DK, Gu X, Zhao Y. Blocking mitochondrial permeability transition prevents p53 mitochondrial translocation during skin tumor promotion. FEBS Letter. 582:1319-1324, 2008.

Hoque R, Menon U, Gonzalez-Toledo E, Gu X, Jaffe SL. CNS Germinoma of the Pituitary and Pineal Regions, Lateral Ventricle, and Fourth Ventricle Presenting in Adulthood. J La State Med Soc. 160:319-321, 2008.

Gu X, Herrera GA. Thrombotic microangiopathy in cocaine abuse-associated malignant hypertension: Report 2 cases with review of the literature. Arch Pathol Lab Med. 131:1817-1020, 2007.

Ayirookuzhi SJ, Chintapalli N, Gu X, Mills GM. A gut reaction. Am J Med. 120:143-145, 2007.